This year, my friends and I decided to participate in a national science competition, called Exploravision. When we started, we thought that we were going to make something that prevented people from getting “roofied” on their first dates with people, which is a widespread concern. However, we found a solution to that that already existed. So we moved to somehow preventing marijuana addictions. But when we spoke to experts on the topic, they said that drugs like fentanyl or crack cocaine would be a better problem to tackle, because they are more potent and life-threatening. The innovation that we thought of to solve this problem is FCRS. FCRS stands for Fentanyl Control and Release System. FCRS gets injected as a chip in the spinal cord.
It is better than just using a regular pill shaped capsule, because pills have only a fleeting effect, while FCRS will have a longer or even lifelong effect on neurotransmitters. It will accomplish blocking the effects of opioids by taking the fentanyl put into the body, storing it, and slowly releasing a set amount of micrograms at a time. In 2018, there were 70,237 people who died of overdose (“Drug Overdose,” 2019). FCRS will make these numbers drastically go down, because even if someone uses a month long prescription of fentanyl patches in one week, the excess fentanyl will stay in the storage of the device until the person who is on opioids needs it again (based on a physician’s prescribed amount). FCRS will also help with recovering from drug addiction, because if you regulate the amount of opioids that you use, and progressively make the amount smaller and smaller, people will eventually stop wanting these opioids just to get pleasure.
FCRS will be put into the spinal cord, because that is where most pain signals get transmitted to the brain. It would work best in the spine, because “The spinal cord is the main source of communication between the body and the brain” (Rosefield, 2016). It is a part of the central nervous system along with the brain. Further, the spinal cord “remembers” pain throughout your body days or even weeks later. As Rosefield states, “When you experience an instance of great pain—you stub your toe incredibly hard, for example, or even break it—the neurons in your spinal cord will carry signals more easily to the nerves in your injured toe for several days, making the toe feel more sensitive” (Rosefield, 2016).
However, it could be slightly difficult to market injecting FCRS into the spinal cord, because the spinal cord is many of the pain signals to the brain are. If it tries to block the high of fentanyl, FCRS could end up making one not feel pain at all, or even not feel any pleasure in anything they do. Also, if the surgeon’s hand slips while they are injecting the chip into someone’s spinal cord, they could end up paralyzing that person or hurting them severely in another way very easily.
During a recent interview with Dr. Amit Om, we learned that using a chip in the spinal cord as our solution to the problem of opioid overdose would not be a very cost-efficient solution to the opioid addiction problem. He stated that implanting a device in the spine requires a whole operation, which would incidentally cost a lot more money, rather than putting it in something like the liver. We thought that this would be a better location for putting FCRS, because opioids such as fentanyl travel through the bloodstream, and go through the liver. Putting it in a place like this would not need extensive procedures. We are also contemplating changing the idea of using a chip in your body to a smart fentanyl patch.
Because the most common prescribed form of fentanyl is a patch, we could change those patches to have our technology inside them. This would enable them to regulate the amount of fentanyl going inside the body, let alone after it is already on its way to someone’s brain.
FCRS would be able to help if the person overdoses, because it could hold the antidote to prevent overdoses. We would incorporate this into our product, because overdoses don’t happen immediately; they take about half an hour to completely happen. Some good things about the smart patch idea would be that it is easy to use, it can have access to the bloodstream, and it can be refilled with the antidote to opioid overdose. However, people can just remove it and then take extra drugs, and overdose.
However, there are still some good things about using a chip in the spine. It would always stay in the spinal cord, and one of the bad things about it is that if we do end up putting the antidote inside the chip, we cannot refill it. Some good things about the smart patch idea would be that it is easy to use, it can have access to the bloodstream, and it can be refilled with the antidote to opioid overdose. One bad thing about using a smart patch would be that people can just remove it and then take extra drugs, and overdose.